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BIOINFORMATICS 101: THE BASICS
This approach works by aligning sequences using a
series of pairwise alignments
1.
two closely related sequences are aligned.
2.
this alignment is fixed.
3.
a third sequence is chosen and aligned to the first alignment.
4.
further sequences are aligned progressively.
The heuristic is fast, but does not guarantee an
optimal alignment.
"
Once a gap,
always a gap
"
PROS AND CONS OF PROGRESSIVE ALIGNMENT
To know more about progressive alignment...
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